ExPASy資料庫簡介-蛋白質序列分析與預測(1)

口述:呂平江 老師

整理:林崇文、鄭詩思、李佩真

 

 

ExPASy的蛋白質體分析工具

1.Protein identification and characterization

2.DNA -> Protein

3.Similarity searches

4.Pattern and profile searches

5.Post-translational modification prediction

6.Topology prediction

7.Primary structure analysis

8.Secondary structure prediction

9.Tertiary structure

10.Sequence alignment

11.Biological text analysis

 

 

 

ExPASy的蛋白質體分析工具

 

 

 

 

 

 

 

 

 

1.      Protein identification and characterization
蛋白質鑑定及特性描述

2.      DNA -> Protein
DNA序列轉為蛋白質序列的工具

3.      Similarity searches
相似序列的搜尋

4.      Pattern and profile searches
模型及圖表的搜尋

5.      Post-translational modification prediction
預測轉譯時的修飾

6.      Topology prediction
拓樸學的預測

7.      Primary structure analysis
主要結構的分析

8.      Secondary structure prediction
次級結構預估

9.      Tertiary structure
三級結構

10.  Sequence alignment
序列比對

11.  Biological text analysis
生物學主題分析

 

文字方塊: 說明:蛋白質體分析的工具種類繁多,以下列出在ExPASy網站中所列出的的工具及其功能中譯,以灰底標示者,代表之後將舉例說明使用方法。

 

 

 

 

 


 

1.Protein identification and characterization

蛋白質鑑定及特性描述

1-1  AACompIdent  - Identify a protein by its amino acid composition

以胺基酸成分鑑定蛋白質。

 

1-2  AACompSim  - Compare the amino acid composition of a Swiss-Prot entry with all other entries

比較Swiss-Prot entry 與其他entries 胺基酸成分分析結果的差異。

 

1-3  MultiIdent  - Identify proteins with pI, Mw, amino acid composition, sequence tag and peptide mass fingerprinting data

以等電點、分子量、胺基酸成分、序列尾端及胜質譜特徵資料鑑定蛋白質。

 

1-4  PeptIdent  - Identify proteins with peptide mass fingerprinting data, pI and Mw Experimentally measured, user-specified peptide masses are compared with the theoretical peptides calculated for all proteins in Swiss-Prot, making extensive use of database annotations

以胜質譜特徵資料、等電點、分子量、胺基酸成分、序列尾端來鑑定蛋白質,以Swiss-Prot中所有蛋白質的理論性胜來比較實驗上的測量以及使用者指定的胜質譜,提供廣泛的資料庫註解功能。

 

1-5  TagIdent  - Identify proteins with pI, Mw and sequence tag, or generate a list of proteins close to a given pI and Mw

以等電點、分子量、序列尾端來鑑定蛋白質,並產生與所給之等電點及分子量最接近的蛋白質列表。

 

1-6  FindMod  - Predict potential protein post-translational modifications and potential single amino acid substitutions in peptides. Experimentally measured peptide masses are compared with the theoretical peptides calculated from a specified Swiss-Prot entry or from a user-entered sequence, and mass differences are used to better characterize the protein of interest.

預測可能的蛋白質轉譯修飾及單一胺基酸可能取代之胜。將實驗上的胜質譜測量結果與指定的Swiss-Prot中的理論性胜或使用者所輸入的序列作比較,集合其差異以作出更佳的蛋白質特性描述。

 

1-7  GlycoMod  - Predict possible oligosaccharide structures that occur on proteins from their experimentally determined masses (can be used for free or derivatized oligosaccharides and for glycopeptides)

以實驗結果的質譜預測可能發生在蛋白質中的低級多醣結構。〈可免費使用並由糖蛋白中的低級多醣來加以引導〉

 

1-8  GlycanMass  - Calculate the mass of an oligosaccharide structure

由一低級多醣蛋白的結構預測其質譜。

 

1-9  FindPept  - Identify peptides that result from unspecific cleavage of proteins from their experimental masses, taking into account artefactual chemical modifications, post-translational modifications (PTM) and protease autolytic cleavage

鑑定一由實驗質譜結果所得的蛋白質胜,並考慮到人工的化學修飾、轉譯修飾(PTM)及蛋白質自體溶解等因素。

 

1-10  PeptideMass  - Calculate masses of peptides and their post-translational modifications for a Swiss-Prot or TrEMBL entry or for a user sequence

Swiss-Prot TrEMBL entry或使用者所提供的序列來預測其胜質譜及轉譯時的修飾。

 

1-11  PeptideCutter  - Predicts potential protease and cleavage sites and sites cleaved by chemicals in a given protein sequence

由所提供的蛋白質序列來預測可能的蛋白質及其化學切開點。

 

1-12  PepMAPPER - Peptide mass fingerprinting tool from UMIST, UK

UMIST UK所提供的胜質譜鑑定工具。

 

1-13  Mascot - Peptide mass fingerprint, sequence query and MS/MS ion search from Matrix Science Ltd., London

Matrix Science Ltd., London搜尋MS/MS離子及進行胜質譜鑑定。

 

1-14  PepSea - Protein identification by peptide mapping or peptide sequencing from Protana, Denmark

以胜繪圖及胜排序來鑑定蛋白質,由Protana, Denmark提供。

 

1-15  PeptideSearch - Peptide mass fingerprint tool from EMBL Heidelberg

EMBL Heidelberg所提供的胜質譜鑑定工具。

 

1-16  ProteinProspector - A variety of tools from UCSF (MS-Fit, MS-Tag, MS-Digest, etc.) for mining sequence databases in conjunction with mass spectrometry experiments [Mirrors at UCL-Ludwig, UK / Ludwig Institute Melbourne (Australia)]

一個由UCSF所提供的多樣性質譜分析工具。

 

1-17 PROWL - Protein chemistry and mass spectrometry resource from Rockefeller and NY Universities [or from Genomic Solutions]

Rockefeller and NY Universities提供蛋白質化學性質及質譜儀資源。

 

1-18 PFMUTS - Shows the possible single and double mutations of a peptide fragment from MALDI peptide mass fingerprinting

MALDI提供,呈現一胜質譜鑑定及胜碎片可能的單一或雙重變化。

 

1-19 CombSearch  - An experimental unified interface to query several protein identification tools accessible on the web

一是試驗性的蛋白質鑑定工具連結介面,相當容易在網上進入。

 


 

2.DNA -> Protein

DNA序列轉為蛋白質序列的工具

2-1  Translate  - Translates a nucleotide sequence to a protein sequence

將一DNA序列轉為蛋白質序列。

 

2-2  Transeq - Nucleotide to protein translation from the EMBOSS package

使用EMBOSS package將核甘酸轉為蛋白質

 

2-3  Graphical Codon Usage Analyser - Displays the codon bias in a graphical manner

以寫實方法呈現密碼子偏差。

 

2-4  BCM search launcher - Six frame translation of nucleotide sequence(s)

核甘酸序列的六種翻譯結構。

 

2-5  Backtranslation - Translates a protein sequence back to a nucleotide sequence

將一蛋白質序列翻譯回核甘酸序列。

 

2-6  Genewise - Compares a protein sequence to a genomic DNA sequence, allowing for introns and frameshifting errors

將蛋白質的序列與基因組的DNA序列做比較,並考慮到intronframeshifting的錯誤。

 

2-7  FSED - Frameshift error detection

偵測frameshifting的錯誤。

 

2-8  LabOnWeb - Elongation, expression profiles and sequence analysis of ESTs using Compugen LEADS clusters

使用Compugen LEADS clusters做延伸、展現圖表及ESTs的序列分析。

2-9  List of gene identification software sites  

       列出基因鑑定的軟體。

 

3.Similarity searches

相似序列的搜尋

3-1  BLAST and WU-BLAST - Interfaces to various versions of the Basic Local Alignment Search Tool

Basic Local Alignment Search 工具的不同翻譯連結。

 

3-2  BLAST  Network Service on ExPASy

ExPASy BLAST  Network伺服器。

 

3-3  BLAST at EMBnet-CH/SIB (Switzerland)

EMBnet-CH/SIB (Switzerland) BLAST

 

3-4  BLAST at NCBI

NCBIBLAST

 

3-5  WU-BLAST at Bork's group in EMBL (Heidelberg) 

EMBL (Heidelberg) Bork's groupWU-BLAST

 

3-6  WU-BLAST and BLAST at the EBI (Hinxton)

EBI (Hinxton) WU-BLASTBLAST

 

3-7  BLAST at PBIL (Lyon)

PBIL (Lyon) BLAST

3-8  Bic ultra-fast rigorous (Smith/Waterman) similarity searches using the Bioccelerator [At DKFZ or at Weizmann]

使用BiocceleratorBic ultra-fast rigorous (Smith/Waterman)來精確搜尋相似的序列。

 

3-9  MPsrch - Smith/Waterman sequence comparison at EBI

位於EBISmith/Waterman序列比對。

 

3-10  DeCypher - Smith/Waterman or FrameSearch search using the DeCypher hardware accelerator

使用DeCypher hardware acceleratorSmith/Waterman FrameSearch序列搜尋。

 

3-11  Fasta3 - FASTA version 3 at the EBI

位於EBI FASTA version 3

 

3-12  FDF - Smith/Waterman type searches on Paracel's Fast Data Finder (FDF) at EMBnet-CH

位於EMBnet-CH Paracel's Fast Data Finder (FDF)上的Smith/Waterman 式搜尋。

 

3-13  PropSearch; searches for structural homologs using a 'properties' approach [At EMBL or at Montpellier]

使用EMBL Montpellier搜尋相近的結構。

 

3-14  SAMBA - Systolic Accelerator for Molecular Biological Applications

心縮加速裝置在分子生物學上的應用。

 

3-15  SAWTED - Structure Assignment With Text Description

描述結構功能。

 

3-16  Scanps - Similarity searches using Barton's algorithm

使用Barton's algorithm搜尋相似序列。

 

 

 

 

 

 


 

4.Pattern and profile searches

模型及圖表的搜尋

4-1  InterPro Scan - Integrated search in PROSITE, Pfam, PRINTS and other family and domain databases

PROSITE, Pfam, PRINTS及其他家族資料庫中合併搜尋。

 

4-2  ScanProsite  - Scans a sequence against PROSITE or a pattern against Swiss-Prot and TrEMBL

掃描一段相對於PROSITESwiss-Prot TrEMBL的序列及圖表。

 

4-3  MotifScan - Scans a sequence against protein profile databases (including PROSITE)

掃描一段相對於protein profile資料庫的序列(包括PROSITE)

 

4-4  Frame-ProfileScan - Scans a short DNA sequence against protein profile databases (including PROSITE)

掃描一段相對於protein profile資料庫的短鏈DNA(包括PROSITE)

 

4-5  Pfam HMM search; scans a sequence against the Pfam protein families db [At Washington University or at Sanger Centre]

Washington UniversitySanger Centre掃描一段相對於Pfam protein families db的序列(包括PROSITE)

 

4-6  FingerPRINTScan - Scans a protein sequence against the PRINTS Protein Fingerprint Database

掃描一段相對於PRINTS Protein Fingerprint資料庫的蛋白質序列。

 

4-7  FPAT - Regular expression searches in protein databases

蛋白質資料庫中的規律表現搜尋。

 

4-8  PRATT - Interactively generates conserved patterns from a series of unaligned proteins; [at EBI / ExPASy  ]

EBI ExPASy產生一unaligned蛋白質的圖表。

 

4-9  PPSEARCH - Scans a sequence against PROSITE (allows a graphical output); at EBI

EBI中掃描一段相對於PROSITE的序列(允許產生圖解)

 

4-10  PROSITE scan - Scans a sequence against PROSITE (allows mismatches); at PBIL

PBIL掃描一段相對於PROSITE的序列(允許錯誤)

 

4-11  PATTINPROT - Scans a protein sequence or a protein database for one or several pattern(s); at PBIL

PBIL掃描一段蛋白質序列或蛋白質資料庫的圖表。

 

4-12  SMART - Simple Modular Architecture Research Tool; at EMBL

位於EMBL的一個簡單的分子結構搜尋工具。

 

4-13  TEIRESIAS - Generate patterns from a collection of unaligned protein or DNA sequences; at IBM

IBM產生一unaligned蛋白質或DNA序列的圖表。

 

4-14  Hits - Relationships between protein sequences and motifs

       蛋白質結構與motifs間的關係。

 


 

5.Post-translational modification prediction

預測轉譯時的修飾

5-1  SignalP - Prediction of signal peptide cleavage sites

預測信號胜  的切點。

 

5-2  ChloroP - Prediction of chloroplast transit peptides

葉綠體傳送胜的預測。

 

5-3  MITOPROT - Prediction of mitochondrial targeting sequences

預測粒腺體的目標序列。

 

5-4  Predotar - Prediction of mitochondrial and plastid targeting sequences

預測粒腺體與質體的目標序列。

 

5-5  NetOGlyc - Prediction of O-GalNAc (mucin type) glycosylation sites in mammalian proteins

預測哺乳動物體內黏蛋白型態的蛋白質醣化位置。

 

5-6  NetNGlyc - Prediction of N-glycosylation sites in human proteins

預測人類體內的N型蛋白質醣化位置。

 

5-7  DictyOGlyc - Prediction of GlcNAc O-glycosylation sites in Dictyostelium

預測黏菌體內的O型蛋白質醣化位置。

 

5-8  YinOYang - O-beta-GlcNAc attachment sites in eukaryotic protein sequences

真核生物蛋白質序列上O-beta-GlcNAc的附著位置。

5-9  big-PI Predictor - GPI Modification Site Prediction

預測GPI的修飾位置。

 

5-10  DGPI - Prediction of GPI-anchor and cleavage sites (Mirror site)

預測GPI的切點與接點位置(鏡像站)

 

5-11  NetPhos - Prediction of Ser, Thr and Tyr phosphorylation sites in eukaryotic proteins

真核生物蛋白質上Ser, Thr Tyr phosphorylation位置的預測。

 

5-12  NetPicoRNA - Prediction of protease cleavage sites in picornaviral proteins

picornaviral proteins上切點的預測。

 

5-13  NMT - Prediction of N-terminal N-myristoylation

N-terminal N-myristoylation的預測。

 

5-14  Sulfinator  - Prediction of tyrosine sulfation sites

酪胺酸硫化位置的預測。

 

5-15  SUMOplot - Prediction of SUMO protein attachment sites

SUMO蛋白質附著位置的預測。

 

6.Topology prediction

拓樸學的預測

6-1  PSORT - Prediction of protein sorting signals and localization sites

預測蛋白質的sorting 信號及localization sites

 

6-2  TargetP - Prediction of subcellular location

預測次細胞的位置。

 

6-3  DAS - Prediction of transmembrane regions in prokaryotes using the Dense Alignment Surface method (Stockholm University)

使用Dense Alignment Surface法預測原核生物的transmembrane區域。

 

6-4  HMMTOP - Prediction of transmembrane helices and topology of proteins (Hungarian Academy of Sciences)

預測蛋白質的transmembrane helices (跨膜螺旋) 拓樸學。

 

6-5  PredictProtein - Prediction of transmembrane helix location and topology (Columbia University)

預測蛋白質的transmembrane helices (跨膜螺旋) 拓樸學。

 

6-6  SOSUI - Prediction of transmembrane regions (TUAT; Tokyo Univ. of Agriculture & Technology)

預測transmembrane區域。

 

6-7  TMAP - Transmembrane detection based on multiple sequence alignment (Karolinska Institut; Sweden)

以複合序列為基礎偵測Transmembrane

 

6-8  TMHMM - Prediction of transmembrane helices in proteins (CBS; Denmark)

預測蛋白質的transmembrane helices (跨膜螺旋)

 

6-9  TMpred - Prediction of transmembrane regions and protein orientation (EMBnet-CH)

預測transmembrane區域及蛋白質方位。

 

6-10  TopPred 2 - Topology prediction of membrane proteins (Stockholm University)

膜蛋白的拓樸學預測。

 


 

7.Primary structure analysis

主要結構的分析

7-1  ProtParam  - Physico-chemical parameters of a protein sequence (amino-acid and atomic compositions, pI, extinction coefficient, etc.)

蛋白質序列的物理及化學變量分析(胺基酸、原子結構、等電點….)

 

7-2  Compute pI/Mw  - Compute the theoretical pI and Mw from a Swiss-Prot or TrEMBL entry or for a user sequence

Swiss-Prot or TrEMBL entry 或使用者提供序列估算其等電點及分子量。

 

7-3  MW, pI, Titration curve - Computes pI, composition and allows to see a titration curve

估算等電點及成分並可看見其滴定曲線圖。

 

7-4  REP - Searches a protein sequence for repeats

搜尋重複的蛋白質序列。

 

7-5  REPRO - De novo repeat detection in protein sequences

重新偵測重複的蛋白質序列。

7-6  Radar - De novo repeat detection in protein sequences

重新偵測重複的蛋白質序列。

 

7-7  SAPS - Statistical analysis of protein sequences at EMBnet-CH [Also available at EBI]

EMBnet-CHEBI的蛋白質序列統計分析。

 

7-8  Coils - Prediction of coiled coil regions in proteins (Lupas's method) at EMBnet-CH [Also available at PBIL]

EMBnet-CH PBIL預測蛋白質的卷曲螺旋區域。

 

7-9  Paircoil - Prediction of coiled coil regions in proteins (Berger's method)

Berger's法預測蛋白質的卷曲螺旋區域。

 

7-10  Multicoil - Prediction of two- and three-stranded coiled coils

預測蛋白質二、三級結構的卷曲螺旋。

 

7-11  2ZIP - Prediction of Leucine Zippers

亮氨酸拉鍊的預測。

 

7-12  PEST - Identification of PEST regions

PEST區域的鑑定。

 

7-13  PESTfind - Identification of PEST regions at EMBnet Austria

EMBnet Austria 鑑定PEST的區域。

 

7-14  HLA_Bind - Prediction of MHC type I (HLA) peptide binding

預測MHC type I (HLA) peptide binding

 

7-15  SYFPEITHI - Prediction of MHC type I and II peptide binding

預測MHC type I II peptide binding

 

7-16  ProtScale  - Amino acid scale representation (Hydrophobicity, other conformational parameters, etc.)

胺基酸刻度圖(構造及其他參數等)

 

7-17  Drawhca - Draw an HCA (Hydrophobic Cluster Analysis) plot of a protein sequence

Hydrophobic Cluster Analysis繪出蛋白質序列。

 

 

7-18  Protein Colourer - Tool for coloring your amino acid sequence

將您的胺基酸序列上色的工具。

 

7-19  Three To One - Tool to convert a three-letter coded amino acid sequence to single letter code

將三碼的胺基酸序列轉為單一密碼的工具。

 

7-20  Colorseq - Tool to highlight (in red) a selected set of residues in a protein sequence

將所選擇的蛋白質序列以紅色加以強調的工具。

 

7-21  HelixWheel / HelixDraw - Representations of a protein fragment as a helical wheel

蛋白質片段的環狀螺旋結構模型。

 

7-22  RandSeq  - Random protein sequence generator

隨機的蛋白質序列產生器。

 

8.Secondary structure prediction

次級結構預估

8-1  AGADIR - An algorithm to predict the helical content of peptides

一個預估胜鏈螺旋結構的演算法。

 

8-2  BCM PSSP - Baylor College of Medicine

Baylor藥物學院。

 

8-3  Prof - Cascaded Multiple Classifiers for Secondary Structure Prediction

Cascaded Multiple Classifiers進行次級結構預估。

 

8-4  GOR I (Garnier et al, 1978) [At PBIL or at SBDS]

GOR I次級結構預估法

 

8-5  GOR II (Gibrat et al, 1987)

GOR II次級結構預估法

 

8-6  GOR IV (Garnier et al, 1996)

GOR IV次級結構預估法

 

8-7  HNN - Hierarchical Neural Network method (Guermeur, 1997)

Hierarchical Neural Network次級結構預估法

 

8-8  Jpred - A consensus method for protein secondary structure prediction at University of Dundee

Dundee大學提供的一般性次級結構預估法。

 

8-9  nnPredict - University of California at San Francisco (UCSF)

San FranciscoCalifornia大學。

 

8-10  PredictProtein - PHDsec, PHDacc, PHDhtm, PHDtopology, PHDthreader, MaxHom, EvalSec from Columbia University

Columbia大學的PHDsec, PHDacc, PHDhtm, PHDtopology, PHDthreader, MaxHom, EvalSec

 

8-11  PSA - BioMolecular Engineering Research Center (BMERC) / Boston

波士頓分子生物學研究中心。

 

8-12  PSIpred - Various protein structure prediction methods at Brunel University

Brunel大學所提供之多種蛋白質結構預估法。

 

8-13  SOPM (Geourjon and Delge, 1994)

SOPM次級結構預估法。

 

8-14  SOPMA (Geourjon and Delge, 1995)

SOPMA次級結構預估法。

 


 

9.Tertiary structure

三級結構

9-1  SWISS-MODEL  - An automated knowledge-based protein modelling server

能自動化產生蛋白質模型的伺服器。

 

9-2  Geno3d - Automatic modelling of protein three-dimensional structure

可自動產生蛋白質3D立體結構模型。

 

9-3  CPHmodels - Automated neural-network based protein modelling server

能自動化產生蛋白質模型的伺服器。

 

9-4  3D-PSSM - Protein fold recognition using 1D and 3D sequence profiles coupled with secondary structure information (Foldfit)

使用次要架構資訊結合的蛋白質摺疊 1D 3D的序列資料的識別 ( Foldfit )

 

9-5  ProSup - Protein structure superimposition

蛋白質結構的疊合。

 

9-6  SWEET - Constructing 3D models of saccharids from their sequences

依照序列建立糖類的3D結構模型。

 

9-7  Swiss-PdbViewer  - A program to display, analyse and superimpose protein 3D structures

可將蛋白質3D結構摺疊、分析並展示的程式。

 

 

 

 

 


 

10.Sequence alignment

序列比對

10-1  Binary (雙重)

 

10-1-1  SIM + LALNVIEW  - Alignment of two protein sequences with SIM, results can be viewed with LALNVIEW

SIM比對二序列,其結果可以LALNVIEW觀看。

 

10-1-2   LALIGN - Finds multiple matching subsegments in two sequences

找到二序列多個相同的部分。

 

10-1-3   Dotlet - A Java applet for sequence comparisons using the dot matrix method

使用Java applet 呈現以dot matrix method比較序列的結果。

 

10-2  Multiple (多重)

 

10-2-1  CLUSTALW [At EBI, PBIL or at EMBnet-CH]

EBI, PBILEMBnet-CH比對序列。

 

10-2-2   T-Coffee [At EMBnet Switzerland or at CMBI]

EMBnet SwitzerlandCMBI比對序列。

10-2-3   ALIGN - at Genestream (IGH)

Genestream (IGH)比對序列。

 

10-2-4   DIALIGN - Multiple sequence alignment based on segment-to-segment comparison, at University of Bielefeld, Germany

德國Bielefeld大學提供的複合序列比對。

 

10-2-5   Match-Box - at University of Namur, Belgium

比利時Namur大學提供的複合序列比對。

 

10-2-6   MSA - at Washington University

Washington大學提供的複合序列比對。

 

10-2-7   Multalin [At INRA or at PBIL]

INRA PBIL比對複數序列。

 

10-2-8   MUSCA - Multiple sequence alignment using pattern discovery, at IBM

IBM 提供的pattern discovery複合序列比對。

 

10-2-9   AMAS - Analyse Multiply Aligned Sequences

用來分析複合序列。

 

10-2-10       Bork's alignment tools - Various tools to enhance the results of multiple alignments (including consensus building).

提升一些聯合結果 (包括一致結果) 的各種工具。

 

10-2-11       CINEMA - Color Interactive Editor for Multiple Alignments

為分析結果著色的工具。

 

10-2-12       ESPript - Tool to print a multiple alignment

複合序列比對結果列印工具。

 

10-2-13       plogo - Sequence logos at CBS/Denmark

丹麥CBSSequence logos

 

10-2-14       GENIO/logo - Sequence logos at Stuttgart/Germany

德國StuttgartSequence logos

 

10-2-15       WebLogo - Sequence logos at Cambridge/UK

英國劍橋的Sequence logos

 

11.Biological text analysis

生物學主題分析

11-1  AcroMed - A computer generated database of biomedical acronyms and the associated long forms extracted from the recent Medline abstracts

生物醫學縮寫及結合字的電子資料庫。

 

11-2  AbXtract - A prototype system for the automatic annotation of functional characteristics in protein families

蛋白質家族功能性特徵自動註解系統的原型。

 

11-3  MedMiner - Extract and organize relevant sentences in the literature based on a gene, gene-gene or gene-drug query

提供有關gene, gene-gene gene-drug的查詢。

 

11-4  Protein Annotator's Assistant - A software system which assists protein annotators in the task of assigning functions to newly sequenced proteins

一個協助蛋白質註解的軟體,可將最新的蛋白質序列加以分配功能。

 

11-5  XplorMed - Explore a set of abstracts derived from a bibliographic search in MEDLINE

MEDLINE搜尋相關資訊。